Effects of Jixueteng on Experimental Periodontitis During Orthodontic Tooth Movement in Rats

Recently, natural ingredients have focused on the inhibition of bacteria-induced alveolar bone resorption in orthodontic treatment. Jixueteng (Jix), a Chinese traditional medicine, contains several kinds flavonoids given their biological properties. We evaluated effects Jix experimental periodontitis during tooth movement (OTM) rats. To this end, 9-week-old male Wistar rats, which were equipped with appliance, orally infected Porphyromonas gingivalis (Pg), while was administered drinking water. A total 28 days after beginning OTM, right side upper jaws scanned micro-computed tomography. These also used as histological specimens and underwent tartrate-resistant acid phosphatase (TRAP) staining. TRAP-positive multinucleated cells counted osteoclasts. As result, distance OTM Pg infection administration (OTM + Jix) group same that sham-infected group. The amount number osteoclasts more significantly decreased than Pg-infected ( P < 0.05). Hence, had little effect inhibited Pg-induced destruction. suggested can support contribute to prevention